http://www.sciencedirect.com/science/article/pii/S0020169314005477
Posts from an inorganic chemistry enthusiast!
Sunday, October 4, 2015
Improvements in the synthesis and understanding of the iodo-bridged intermediate en route to the Pt(IV) prodrug satraplatin #chempaperaday 233
Satraplatin is a Pt(IV) prodrug and the route to satraplatin is still in debate. In this article the authors propose a iodo-bridged intermediate and an improved synthesis to this intermediate. Really nice work and characterization methods.
http://www.sciencedirect.com/science/article/pii/S0020169314005477
http://www.sciencedirect.com/science/article/pii/S0020169314005477
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atraplatin, also known as JM216, is a platinum compound that is currently under investigation as one treatment of patients with advanced prostate cancer who have failed previous chemotherapy. Satraplatin
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