Thursday, June 1, 2017

Protein Metalation by Anticancer Metallodrugs: A Joint ESI MS and XRD Investigative Strategy #chempaperaday 301

This is a Concept article. From my own research, I very well know that what crystallizes sometimes is not what is happening in the solution. I guess this is somewhat applicable to drug-protein interactions too. After all, most of the crystals obtained in this field are grown in buffers, crystallization mediums etc. In this short paper, they show some examples where ESI MS is used to further investigate metal-protein adducts that are structurally characterized.

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