Sunday, January 26, 2014

#chempaperaday Day 10/365: "Metal-based anticancer drugs: From a past anchored in platinum chemistry to a post-genomic future of diverse chemistry and biology"

More metal based antitumor complexes? This is a short but good review on them. It is free to read.

Here I used PyMOL to see how cisplatin kinks the duplex by binding DNA in a covalent manner. Its color is magenta (the one on the right). I tried my best but it is really hard to see.

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